Ontology highlight
ABSTRACT:
SUBMITTER: Gerstein MB
PROVIDER: S-EPMC3142569 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20101222 6012
We systematically generated large-scale data sets to improve genome annotation for the nematode Caenorhabditis elegans, a key model organism. These data sets include transcriptome profiling across a developmental time course, genome-wide identification of transcription factor-binding sites, and maps of chromatin organization. From this, we created more complete and accurate gene models, including alternative splice forms and candidate noncoding RNAs. We constructed hierarchical networks of trans ...[more]