Ontology highlight
ABSTRACT:
SUBMITTER: Remijsen Q
PROVIDER: S-EPMC3193439 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Remijsen Quinten Q Vanden Berghe Tom T Wirawan Ellen E Asselbergh Bob B Parthoens Eef E De Rycke Riet R Noppen Sam S Delforge Michel M Willems Jean J Vandenabeele Peter P
Cell research 20101109 2
Neutrophil extracellular traps (NETs) are extracellular chromatin structures that can trap and degrade microbes. They arise from neutrophils that have activated a cell death program called NET cell death, or NETosis. Activation of NETosis has been shown to involve NADPH oxidase activity, disintegration of the nuclear envelope and most granule membranes, decondensation of nuclear chromatin and formation of NETs. We report that in phorbol myristate acetate (PMA)-stimulated neutrophils, intracellul ...[more]