Ontology highlight
ABSTRACT:
SUBMITTER: Friberg H
PROVIDER: S-EPMC3216538 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Scientific reports 20110801
Serotype-cross-reactive memory T cells responding to secondary dengue virus (DENV) infection are thought to contribute to disease. However, epitope-specific T cell responses have not been thoroughly compared between subjects with primary versus secondary DENV infection. We studied CD8(+) T cells specific for the HLA-A*1101-restricted NS3(133) epitope in a cohort of A11(+) DENV-infected patients throughout acute illness and convalescence. We compared the expansion, serotype-cross-reactivity, and ...[more]