Relationship between ambulatory BP and clinical outcomes in patients with hypertensive CKD.

ABSTRACT:

Background and objectives

Abnormal ambulatory BP (ABP) profiles are commonplace in CKD, yet the prognostic value of ABP for renal and cardiovascular outcomes is uncertain. This study assessed the relationship of baseline ABP profiles with CKD progression and subsequent cardiovascular outcomes to determine the prognostic value of ABP beyond that of clinic BP measurements.

Design, setting, participants, & measurements

Between 2002 and 2003, 617 African Americans with hypertensive CKD treated to a clinic BP goal of <130/80 mmHg were enrolled in this prospective, observational study. Participants were followed for a median of 5 years. Primary renal outcome was a composite of doubling of serum creatinine, ESRD, or death. The primary cardiovascular outcome was a composite of myoca

SUBMITTER: Gabbai FB 

PROVIDER: S-EPMC3488952 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature