Exploration of the core metabolism of symbiotic bacteria.

ABSTRACT:

Background

A large number of genome-scale metabolic networks is now available for many organisms, mostly bacteria. Previous works on minimal gene sets, when analysing host-dependent bacteria, found small common sets of metabolic genes. When such analyses are restricted to bacteria with similar lifestyles, larger portions of metabolism are expected to be shared and their composition is worth investigating. Here we report a comparative analysis of the small molecule metabolism of symbiotic bacteria, exploring common and variable portions as well as the contribution of different lifestyle groups to the reduction of a common set of metabolic capabilities.

Results

We found no reaction shared by all the bacteria analysed. Disregarding those with the smallest genomes, we still do n

SUBMITTER: Klein CC 

PROVIDER: S-EPMC3543179 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature