Estimated mean sojourn time associated with hemoccult SENSA for detection of proximal and distal colorectal cancer.

ABSTRACT:

Background

Sojourn time is the length of the preclinical screen-detectable phase, a period when a test can detect asymptomatic disease. Mean sojourn time (MST) is an important factor in determining appropriate screening intervals. Available estimates of MST for colorectal cancer (CRC) are imprecise and are associated with the older Hemoccult II test. This article presents MST estimates associated with the newer Hemoccult SENSA test and describes differences in MST by the location of cancer in the colorectum and age at the time of screening.

Methods

MST was estimated from a cohort of 42,079 patients who underwent Hemoccult SENSA between January 1, 1997 and December 31, 2010. The precision of MST estimates was improved by incorporating information from a meta-analysis of the s

SUBMITTER: Zheng W 

PROVIDER: S-EPMC3557510 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature