Novel insights into the bovine polled phenotype and horn ontogenesis in Bovidae.

ABSTRACT: Despite massive research efforts, the molecular etiology of bovine polledness and the developmental pathways involved in horn ontogenesis are still poorly understood. In a recent article, we provided evidence for the existence of at least two different alleles at the Polled locus and identified candidate mutations for each of them. None of these mutations was located in known coding or regulatory regions, thus adding to the complexity of understanding the molecular basis of polledness. We confirm previous results here and exhaustively identify the causative mutation for the Celtic allele (PC) and four candidate mutations for the Friesian allele (PF). We describe a previously unreported eyelash-and-eyelid phenotype associated with regular polledness, and present unique histological and gene

SUBMITTER: Allais-Bonnet A 

PROVIDER: S-EPMC3661542 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature