Molecular characterization of human adenovirus infection in Thailand, 2009-2012.

ABSTRACT:

Background

Human adenovirus (HAdV) can cause a wide spectrum of human diseases worldwide.

Methods

Using PCR and sequence analysis, we investigated HAdV infection prevalence in the Thai population for four years from January 2009 to December 2012. We collected Nasopharyngeal swab/aspirate (NP) specimens from patients in Bangkok, Khon Kaen, and Nakhon Si Thammarat province and fecal specimens only from Bangkok and Khon Kaen province.

Results

We observed HAdV infection in 1.04% (82/7,921) of NP samples and in 5.84% (76/1,301) of fecal specimens. HAdV-B3 (32%) and HAdV-C1 (31%) were the genotypes most commonly associated with NP specimens followed by HAdV-C2 (13%) and HAdV-C5 (12%). In fecal specimens, we found that 25% harbored HAdV-F41 followed by HAdV-C1 (18%), HAdV-C2

SUBMITTER: Sriwanna P 

PROVIDER: S-EPMC3693972 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature