Dataset Information

Diagnostic evaluation of ocular toxocariasis using high-penetration optical coherence tomography.

ABSTRACT:

Purpose

To study a case with intraretinal Toxocara larvae in a granuloma using high-penetration optical coherence tomography (HP-OCT).

Methods

A 50-year-old man, who was referred to our clinic with ocular toxocariasis, initially presented with granuloma formation in the retina. We followed the treatment-associated changes in the toxocariasis lesion by a series of examinations using HP-OCT before and after a systemic corticosteroid and anthelmintic therapy.

Results

The posterior pole granuloma initially appeared as a yellowish-white intraretinal lesion with an exudative focus and dye leakage seen on angiography. After therapy, the lesion was no longer exudative. During treatment-free periods, an intraretinal lesion was seen protruding from the retinal surface into the vitreous cavity. HP-OCT confirmed the elevated lesion protruding from the retinal surface into the vitreous cavity. With treatment, the protruding focus flattened during the following 8 months, but the lesion recurred after the treatment stopped.

Conclusions

The findings and clinical course strongly suggested ocular toxocariasis. The protruding retinal lesion may have been an ocular manifestation of toxocariasis. HP-OCT was useful in the follow-up and diagnosis.

SUBMITTER: Hashida N

PROVIDER: S-EPMC3934803 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Publications

Diagnostic evaluation of ocular toxocariasis using high-penetration optical coherence tomography.

Hashida Noriyasu N Nakai Kei K Nishida Kohji K

Case reports in ophthalmology 20140108 1

<h4>Purpose</h4>To study a case with intraretinal Toxocara larvae in a granuloma using high-penetration optical coherence tomography (HP-OCT).<h4>Methods</h4>A 50-year-old man, who was referred to our clinic with ocular toxocariasis, initially presented with granuloma formation in the retina. We followed the treatment-associated changes in the toxocariasis lesion by a series of examinations using HP-OCT before and after a systemic corticosteroid and anthelmintic therapy.<h4>Results</h4>The poste ...[more]

PMID: 24575034

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Project description:PurposeTo explore the consistency and efficacy of optical coherence tomography (OCT) for the evaluation of ocular torsion angle compared to fundus photography in children.MethodPatients who had undergone fundus photography and OCT within 1 day were included in this study. The fundus photographs were taken using a fundus camera and then imported into the Adobe Photoshop 2021 software. The fovea-disc angle (FDA) was calculated manually. OCT was used to automatically detect the centers of the optic disc and fovea, and the software then calculated the FDA on the same device. The means and ranges of variables were calculated in this study. Group differences were assessed using the paired t-test. Statistical significance was determined when P-values were <0.05. Bland-Altman plots were constructed to verify the agreement of the FDAs measured by fundus photography and OCT respectively.ResultsA total of 100 patients were included and the objective measurements of the ocular torsion angles via OCT and fundus photography were similar. The mean FDA of 32 patients aged 2-6 years old was -7.84 ± 4.67° via fundus photography and -6.71 ± 6.19° via OCT. The mean FDA of 68 patients aged 6-18 years old was -8.47 ± 5.22° via fundus photography and -8.97 ± 5.41° via OCT. According to the receiver operational characteristic (ROC) curves of the FDA for diagnosing ocular extorsion, the area under the ROC curve was greatest for OCT (0.943, 95% CI: 0.902-0.984), followed by fundus photography (0.92, 95% CI: 0.86-0.979). With the Youden method, the optimal cut-off point for diagnosing ocular extorsion with OCT was -6.35°. OCT demonstrated a sensitivity of 100% and a specificity of 49.2%. Furthermore, the optimal cut-off point for diagnosing ocular extorsion with fundus photography was -6.5°.ConclusionThe comparison of FDAs showed good agreement between fundus photography and OCT. Thus, OCT can evaluate ocular torsion angle effectively in children.

Dataset Information

Diagnostic evaluation of ocular toxocariasis using high-penetration optical coherence tomography.

Purpose

Methods

Results

Conclusions

Publications

Diagnostic evaluation of ocular toxocariasis using high-penetration optical coherence tomography.

Similar Datasets

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