Breast cancer screening, area deprivation, and later-stage breast cancer in Appalachia: does geography matter?

ABSTRACT:

Objective

To model the relationship of an area-based measure of a breast cancer screening and geographic area deprivation on the incidence of later stage breast cancer (LSBC) across a diverse region of Appalachia.

Data source

Central cancer registry data (2006-2008) from three Appalachian states were linked to Medicare claims and census data.

Study design

Exploratory spatial analysis preceded the statistical model based on negative binomial regression to model predictors and effect modification by geographic subregions.

Principal findings

Exploratory spatial analysis revealed geographically varying effects of area deprivation and screening on LSBC. In the negative binomial regression model, predictors of LSBC included receipt of screening, area deprivation, sup

SUBMITTER: Anderson RT 

PROVIDER: S-EPMC3976186 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature