Gene expression profiles of patients with cerebral hematoma following spontaneous intracerebral hemorrhage.

ABSTRACT: The present study aimed to investigate the gene functions and expression profiles in perihematomal (PH) brain regions following spontaneous intracerebral hemorrhage. The gene expression profiles were downloaded from the Gene Expression Omnibus database under accession number GSE24265, which includes 11 brain samples from different regions, including four samples from PH areas, four from contralateral grey matter (CG) and three from contralateral white matter (CW). The gene expression profiles were pre-processed and the differentially expressed genes (DEGs) between PH and CG tissue, and PH and CW tissue were identified using R packages. The expression of genes in different tissues was analyzed by hierarchical clustering. Then, the interaction network between the DEGs was constructed using S

SUBMITTER: Yang T 

PROVIDER: S-EPMC4148373 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature