Prediction of DNase I hypersensitive sites by using pseudo nucleotide compositions.
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ABSTRACT:
SUBMITTER: Feng P
PROVIDER: S-EPMC4152949 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Prediction of DNase I hypersensitive sites by using pseudo nucleotide compositions.
Feng Pengmian P Jiang Ning N Liu Nan N
TheScientificWorldJournal 20140819
DNase I hypersensitive sites (DHS) associated with a wide variety of regulatory DNA elements. Knowledge about the locations of DHS is helpful for deciphering the function of noncoding genomic regions. With the acceleration of genome sequences in the postgenomic age, it is highly desired to develop cost-effective computational methods to identify DHS. In the present work, a support vector machine based model was proposed to identify DHS by using the pseudo dinucleotide composition. In the jackkni ...[more]
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