Comparative genome analysis of entomopathogenic fungi reveals a complex set of secreted proteins.

ABSTRACT:

Background

Metarhizium anisopliae is an entomopathogenic fungus used in the biological control of some agricultural insect pests, and efforts are underway to use this fungus in the control of insect-borne human diseases. A large repertoire of proteins must be secreted by M. anisopliae to cope with the various available nutrients as this fungus switches through different lifestyles, i.e., from a saprophytic, to an infectious, to a plant endophytic stage. To further evaluate the predicted secretome of M. anisopliae, we employed genomic and transcriptomic analyses, coupled with phylogenomic analysis, focusing on the identification and characterization of secreted proteins.

Results

We determined the M. anisopliae E6 genome sequence and compared this sequence to other entomopatho

SUBMITTER: Staats CC 

PROVIDER: S-EPMC4246632 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature