Prevalence of asymptomatic carotid artery stenosis in the general population: an individual participant data meta-analysis.

ABSTRACT:

Background and purpose

In the discussion on the cost-effectiveness of screening, precise estimates of severe asymptomatic carotid stenosis are vital. Accordingly, we assessed the prevalence of moderate and severe asymptomatic carotid stenosis by age and sex using pooled cohort data.

Methods

We performed an individual participant data meta-analysis (23 706 participants) of 4 population-based studies (Malmö Diet and Cancer Study, Tromsø, Carotid Atherosclerosis Progression Study, and Cardiovascular Health Study). Outcomes of interest were asymptomatic moderate (> or =50%) and severe carotid stenosis (> or =70%).

Results

Prevalence of moderate asymptomatic carotid stenosis ranged from 0.2% (95% CI, 0.0% to 0.4%) in men aged <50 years to 7.5% (5.2% to 10.5%) in men aged >

SUBMITTER: de Weerd M 

PROVIDER: S-EPMC4254855 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature