Survival of Mexican children with acute myeloid leukaemia who received early intensification chemotherapy and an autologous transplant.

ABSTRACT:

Background

In Mexico and other developing countries, few reports of the survival of children with acute leukaemia exist. Objective. We aimed at comparing the disease-free survival of children with acute myeloid leukaemia who, in addition to being treated with the Latin American protocol of chemotherapy and an autologous transplant, either underwent early intensified chemotherapy or did not undergo such treatment.

Procedure

This was a cohort study with a historical control group, forty patients, less than 16 years old. Group A (20 patients), diagnosed in the period 2005-2007, was treated with the Latin American protocol of chemotherapy with an autologous transplant plus early intensified chemotherapy: high doses of cytarabine and mitoxantrone. Group B (20 patients), diagnosed

SUBMITTER: Jimenez-Hernandez E 

PROVIDER: S-EPMC4363903 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature