What is the effect of matrices on cartilage repair? A systematic review.

ABSTRACT:

Background

Articular cartilage has minimal endogenous ability to undergo repair. Multiple chondral restoration strategies have been attempted with varied results.

Questions/purposes

The purpose of our review was to determine: (1) Does articular chondrocyte transplantation or matrix-assisted articular chondrocyte transplantation provide better patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue compared with microfracture in prospective comparative studies of articular cartilage repair; and (2) which available matrices for matrix-assisted articular chondrocyte transplantation show the best patient-reported outcomes scores, MRI morphologic measurements, or histologic quality of repair tissue?

Methods

We conducted a syst

SUBMITTER: Wylie JD 

PROVIDER: S-EPMC4385356 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature