Anhedonia in melancholic and non-melancholic depressive disorders.

ABSTRACT:

Background

Anhedonia represents a core symptom of major depression and may be a potential marker for melancholia. However, current understanding of this construct in depressive sub-types is limited.

Method

Participants were recruited from the Black Dog Institute (Sydney) and Massachusetts General Hospital (Boston). Diagnostic groups were derived on the basis of agreement between clinician and DSM-IV diagnosis from structured interviews. Currently depressed unipolar melancholic, non-melancholic and healthy control participants were administered a probabilistic reward task (PRT) to assess a behavioural correlate of anhedonia-blunted reward-based learning. Self-reported measures of anhedonia, approach and avoidance motivation were completed by the Sydney sample.

Results

SUBMITTER: Fletcher K 

PROVIDER: S-EPMC4519400 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature