Bronchoscopic lung volume reduction by endobronchial valve in advanced emphysema: the first Asian report.

ABSTRACT:

Purpose

Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed.

Patients and methods

This prospective open-label single-arm clinical trial examined the clinical efficacy and the safety of EBV in 43 consecutive patients (mean age 68.4±7.5, forced expiratory volume in 1 second [FEV1] 24.5%±10.7% predicted, residual volume 208.7%±47.9% predicted) with severe emphysema with complete fissure and no collateral ventilation in a tertiary referral hospital in Korea.

Results

Compared to baseline, the patients exhibited significant improvements 6 months after EBV therapy in terms of FEV1 (from 0.

SUBMITTER: Park TS 

PROVIDER: S-EPMC4524390 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature