DisVis: quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes.

ABSTRACT:

Unlabelled

We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage.

Availability and implementation

The source code with documentation is freely available from https://github.com/haddocking/disvis.

Contact

[e-mail]

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: van Zundert GC 

PROVIDER: S-EPMC4576694 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature