Ontology highlight
ABSTRACT:
SUBMITTER: Lee WH
PROVIDER: S-EPMC4650931 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Lee Won-Hee WH Choi Hyun-Il HI Hong Sung-Wook SW Kim Kwang-Sun KS Gho Yong Song YS Jeon Seong Gyu SG
Experimental & molecular medicine 20150911
The emergence of multidrug-resistant Klebsiella pneumoniae highlights the need to develop preventive measures to ameliorate Klebsiella infections. Bacteria-derived extracellular vesicles (EVs) are spherical nanometer-sized proteolipids enriched with outer membrane proteins. Gram-negative bacteria-derived EVs have gained interest for use as nonliving complex vaccines. In the present study, we evaluated whether K. pneumoniae-derived EVs confer protection against bacteria-induced lethality. K. pneu ...[more]