Non-invasive screening of diabetics in primary care for NAFLD and advanced fibrosis by MRI and MRE.

ABSTRACT:

Background

Current guidelines do not recommend screening for non-alcoholic fatty liver disease (NAFLD) or advanced fibrosis. Patients with type 2 diabetes mellitus (T2DM) are known to be at increased risk for NAFLD and advanced fibrosis.

Aim

To assess the feasibility in diabetics in a primary care setting of screening for NAFLD and advanced fibrosis, by using non-invasive magnetic resonance imaging (MRI) to estimate the hepatic proton density fat fraction (MRI-PDFF) and magnetic resonance elastography (MRE) to estimate hepatic stiffness.

Methods

We performed a cross-sectional analysis of a prospective study that included 100 (53% men) consecutively enrolled diabetics who did not have any other aetiology of liver disease. All patients underwent a standardised research

SUBMITTER: Doycheva I 

PROVIDER: S-EPMC4673036 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature