Associations between anxiety and depression symptoms and cognitive testing and neuroimaging in type 2 diabetes.

ABSTRACT:

Aims

Anxiety, depression, accelerated cognitive decline, and increased risk of dementia are observed in individuals with type 2 diabetes. Anxiety and depression may contribute to lower performance on cognitive tests and differences in neuroimaging observed in individuals with type 2 diabetes.

Methods

These relationships were assessed in 655 European Americans with type 2 diabetes from 504 Diabetes Heart Study families. Participants completed cognitive testing, brain magnetic resonance imaging, the Brief Symptom Inventory Anxiety subscale, and the Center for Epidemiologic Studies Depression-10.

Results

In analyses adjusted for age, sex, educational attainment, and use of psychotropic medications, individuals with comorbid anxiety and depression symptoms had lower perfo

SUBMITTER: Raffield LM 

PROVIDER: S-EPMC4698057 | biostudies-literature | 2016 Jan-Feb

REPOSITORIES: biostudies-literature