Statistical Methods for Estimating the Cumulative Risk of Screening Mammography Outcomes.

ABSTRACT:

Background

This study illustrates alternative statistical methods for estimating cumulative risk of screening mammography outcomes in longitudinal studies.

Methods

Data from the US Breast Cancer Surveillance Consortium (BCSC) and the Nijmegen Breast Cancer Screening Program in the Netherlands were used to compare four statistical approaches to estimating cumulative risk. We estimated cumulative risk of false-positive recall and screen-detected cancer after 10 screening rounds using data from 242,835 women ages 40 to 74 years screened at the BCSC facilities in 1993-2012 and from 17,297 women ages 50 to 74 years screened in Nijmegen in 1990-2012.

Results

In the BCSC cohort, a censoring bias model estimated bounds of 53.8% to 59.3% for false-positive recall and 2.4% to 7

SUBMITTER: Hubbard RA 

PROVIDER: S-EPMC4779749 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature