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Responses of Saccharomyces cerevisiae Strains from Different Origins to Elevated Iron Concentrations.


ABSTRACT: Iron is an essential micronutrient for all eukaryotic organisms. However, the low solubility of ferric iron has tremendously increased the prevalence of iron deficiency anemia, especially in women and children, with dramatic consequences. Baker's yeast Saccharomyces cerevisiae is used as a model eukaryotic organism, a fermentative microorganism, and a feed supplement. In this report, we explore the genetic diversity of 123 wild and domestic strains of S. cerevisiae isolated from different geographical origins and sources to characterize how yeast cells respond to elevated iron concentrations in the environment. By using two different forms of iron, we selected and characterized both iron-sensitive and iron-resistant yeast strains. We observed that when the iron concentration in the medium

SUBMITTER: Martinez-Garay CA 

PROVIDER: S-EPMC4784042 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature