Central Pressure Appraisal: Clinical Validation of a Subject-Specific Mathematical Model.

ABSTRACT:

Introduction

Current evidence suggests that aortic blood pressure has a superior prognostic value with respect to brachial pressure for cardiovascular events, but direct measurement is not feasible in daily clinical practice.

Aim

The aim of the present study is the clinical validation of a multiscale mathematical model for non-invasive appraisal of central blood pressure from subject-specific characteristics.

Methods

A total of 51 young male were selected for the present study. Aortic systolic and diastolic pressure were estimated with a mathematical model and were compared to the most-used non-invasive validated technique (SphygmoCor device, AtCor Medical, Australia). SphygmoCor was calibrated through diastolic and systolic brachial pressure obtained with a sphygmoma

SUBMITTER: Tosello F 

PROVIDER: S-EPMC4806836 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature