Formation of C(sp(2))-boronate esters by borylative cyclization of alkynes using BCl3.

ABSTRACT: BCl3 is an inexpensive electrophile which induces the borylative cyclization of a wide range of substituted alkynes to regioselectively form polycycles containing synthetically versatile C(sp(2) )boronate esters. It proceeds rapidly, with good yields and is compatible with a range of functional groups and substitution patterns. Intermolecular 1,2-carboboration of alkynes is also achieved using BCl3 to generate trisubstituted vinyl boronate esters.

SUBMITTER: Warner AJ 

PROVIDER: S-EPMC4832827 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature