Cognitive decline and quality of life in incident Parkinson's disease: The role of attention.

ABSTRACT:

Introduction

Parkinson's disease dementia (PDD) is associated with poorer quality of life (QoL). Prior to the onset of PDD, many patients experience progressive cognitive impairment. There is a paucity of longitudinal studies investigating the effects of cognitive decline on QoL. This study aimed to determine the longitudinal impact of cognitive change on QoL in an incident PD cohort.

Methods

Recently diagnosed patients with PD (n = 212) completed a schedule of neuropsychological assessments and QoL measures; these were repeated after 18 (n = 190) and 36 months (n = 158). Mild cognitive impairment (PD-MCI) was classified with reference to the Movement Disorder Society criteria. Principal component analysis was used to reduce 10 neuropsychological tests to three cognitive fac

SUBMITTER: Lawson RA 

PROVIDER: S-EPMC4906150 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature