Electrical impedance myography in facioscapulohumeral muscular dystrophy.

ABSTRACT:

Introduction

In this study we determined the reliability and validity of electrical impedance myography (EIM) in facioscapulohumeral muscular dystrophy (FSHD).

Methods

We performed a prospective study of EIM on 16 bilateral limb and trunk muscles in 35 genetically defined and clinically affected FSHD patients (reliability testing on 18 patients). Summary scores based on body region were derived. Reactance and phase (50 and 100 kHz) were compared with measures of strength, FSHD disease severity, and functional outcomes.

Results

Participants were mostly men, mean age 53.0 years, and included a full range of severity. Limb and trunk muscles showed good to excellent reliability [intraclass correlation coefficients (ICC) 0.72-0.99]. Summary scores for the arm, leg, and tru

SUBMITTER: Statland JM 

PROVIDER: S-EPMC4972708 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature