Comparison of clinical MRI liver iron content measurements using signal intensity ratios, R ₂ and R ₂.

ABSTRACT:

Purpose

To compare three types of MRI liver iron content (LIC) measurement performed in daily clinical routine in a single center over a 6-year period.

Methods

Patients undergoing LIC MRI-scans (1.5T) at our center between January 1, 2008 and December 31, 2013 were retrospectively included. LIC was measured routinely with signal intensity ratio (SIR) and MR-relaxometry (R ₂ and R ₂*) methods. Three observers placed regions-of-interest. The success rate was the number of correctly acquired scans over the total number of scans. Interobserver agreement was assessed with intraclass correlation coefficients (ICC) and Bland-Altman analysis, correlations between LIC_SIR, R ₂, R ₂*, and serum values with Spearman's rank correlati

SUBMITTER: Runge JH 

PROVIDER: S-EPMC5059419 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature