Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study.

ABSTRACT:

Introduction

Exercise is an important countermeasure to limb muscle dysfunction in COPD. The two major training modalities in COPD rehabilitation, endurance training (ET) and resistance training (RT), may both be efficient in improving muscle strength, exercise capacity, and health-related quality of life, but the effects on quadriceps muscle characteristics have not been thoroughly described.

Methods

Thirty COPD patients (forced expiratory volume in 1 second: 56% of predicted, standard deviation [SD] 14) were randomized to 8 weeks of ET or RT. Vastus lateralis muscle biopsies were obtained before and after the training intervention to assess muscle morphology and metabolic and angiogenic factors. Symptom burden, exercise capacity (6-minute walking and cycle ergometer tests)

SUBMITTER: Iepsen UW 

PROVIDER: S-EPMC5087783 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature