LocExpress: a web server for efficiently estimating expression of novel transcripts.

ABSTRACT:

Background

The temporal and spatial-specific expression pattern of a transcript in multiple tissues and cell types can indicate key clues about its function. While several gene atlas available online as pre-computed databases for known gene models, it's still challenging to get expression profile for previously uncharacterized (i.e. novel) transcripts efficiently.

Results

Here we developed LocExpress, a web server for efficiently estimating expression of novel transcripts across multiple tissues and cell types in human (20 normal tissues/cells types and 14 cell lines) as well as in mouse (24 normal tissues/cell types and nine cell lines). As a wrapper to RNA-Seq quantification algorithm, LocExpress efficiently reduces the time cost by making abundance estimation calls increa

SUBMITTER: Hou M 

PROVIDER: S-EPMC5260097 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature