Refractory status epilepticus in children with and without prior epilepsy or status epilepticus.

ABSTRACT:

Objective

To compare refractory convulsive status epilepticus (rSE) management and outcome in children with and without a prior diagnosis of epilepsy and with and without a history of status epilepticus (SE).

Methods

This was a prospective observational descriptive study performed from June 2011 to May 2016 on pediatric patients (1 month-21 years of age) with rSE.

Results

We enrolled 189 participants (53% male) with a median (25th-75th percentile) age of 4.2 (1.3-9.6) years. Eighty-nine (47%) patients had a prior diagnosis of epilepsy. Thirty-four (18%) patients had a history of SE. The time to the first benzodiazepine was similar in participants with and without a diagnosis of epilepsy (15 [5-60] vs 16.5 [5-42.75] minutes, p = 0.858). Patients with a diagnosis of epi

SUBMITTER: Sanchez Fernandez I 

PROVIDER: S-EPMC5272971 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature