Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort.

ABSTRACT:

Objective

To assess the association between Mediterranean-type diet (MeDi) and change in brain MRI volumetric measures and mean cortical thickness across a 3-year period in older age (73-76 years).

Methods

We focused on 2 longitudinal brain volumes (total and gray matter; n = 401 and 398, respectively) plus a longitudinal measurement of cortical thickness (n = 323), for which the previous cross-sectional evidence of an association with the MeDi was strongest. Adherence to the MeDi was calculated from data gathered from a food frequency questionnaire at age 70, 3 years prior to the baseline imaging data collection.

Results

In regression models adjusting for relevant demographic and physical health indicators, we found that lower adherence to the MeDi was associated wit

SUBMITTER: Luciano M 

PROVIDER: S-EPMC5278943 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature