Pigment retinopathy in warmblood horses with equine degenerative myeloencephalopathy and equine motor neuron disease.

ABSTRACT:

Objective

A pigment retinopathy has been reported in adult horses with equine motor neuron disease (EMND) arising from chronic α-tocopherol (α-TP) deficiency. A pigment retinopathy has not been identified in horses with neuroaxonal dystrophy/equine degenerative myeloencephalopathy (NAD/EDM) that affects genetically susceptible young horses with α-TP deficiency. The objective of this report is to describe, for the first time, a pigment retinopathy in a family of α-TP-deficient Warmbloods (WB) with clinically apparent NAD/EDM or EMND.

Animals and procedures

Twenty-five WB horses from one farm underwent complete neurologic and ophthalmic examinations and serum α-TP concentrations were assessed. Two of the most severely ataxic horses were euthanized and postmortem examinations p

SUBMITTER: Finno CJ 

PROVIDER: S-EPMC5292316 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature