Tailored algorithms for hepatocellular carcinoma surveillance: Is one-size-fits-all strategy outdated?

ABSTRACT:

Purpose of review

Current clinical practice guidelines recommend regular hepatocellular carcinoma (HCC) surveillance with biannual ultrasound with or without serum alpha-fetoprotein uniformly applied to all patients with cirrhosis. However, clinical implementation of this one-size-fits-all strategy has been challenging as evidenced by very low application rate below 20% due to various reasons, including suboptimal performance of the surveillance modalities.

Recent findings

Newly emerging imaging techniques such as abbreviated MRI (AMRI) and molecular HCC risk biomarkers have increasingly become available for clinical evaluation and implementation. These technologies may have a potential to reshape HCC surveillance by enabling tailored strategies. This would involve performin

SUBMITTER: Goossens N 

PROVIDER: S-EPMC5358664 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature