MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways.

ABSTRACT:

Summary

MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes.

Availability and implementation

MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/.

Contact

[e-mail] .

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Rodriguez-Martinez A 

PROVIDER: S-EPMC5408820 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature