Transcriptional organization of genes for protocatechuate and quinate degradation from Acinetobacter sp. strain ADP1.

ABSTRACT: Quinate and protocatechuate are both abundant plant products and can serve, along with a large number of other aromatic or hydroaromatic compounds, as growth substrates for Acinetobacter sp. strain ADP1. The respective genes are part of the chromosomal dca-pca-qui-pob-hca cluster encoding these pathways. The adjacent pca and qui gene clusters, which encode enzymes for protocatechuate breakdown via the beta-ketoadipate pathway and for the conversion of quinate or shikimate to protocatechuate, respectively, have the same direction of transcription and are both expressed inducibly in response to protocatechuate. The pca genes are governed by the transcriptional activator-repressor PcaU. The mechanism governing qui gene expression was previously unknown. Here we report data suggesting the exis

SUBMITTER: Dal S 

PROVIDER: S-EPMC546756 | biostudies-literature | 2005 Feb

REPOSITORIES: biostudies-literature