Increased Risk of Thai Childhood Acute Lymphoblastic Leukemia with the MiR196a2 T>C Polymorphism
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ABSTRACT:
SUBMITTER: Rakmanee S
PROVIDER: S-EPMC5494224 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Increased Risk of Thai Childhood Acute Lymphoblastic Leukemia with the MiR196a2 T>C Polymorphism
Rakmanee Sarinthorn S Pakakasama Samart S Hongeng Suradej S Sanguansin Sirima S Thongmee Acharawan A Pongstaporn Wanida W
Asian Pacific journal of cancer prevention : APJCP 20170401 4
Objectives: This study assessed associations of the miR196a2 (rs11614913) T>C polymorphism withsusceptibility to childhood acute lymphoblastic leukemia (ALL) and clinical outcomes. Materials and Methods: Blood DNA samples from 104 childhood ALL patients and 180 healthy children were studied for the miR-196a2 (rs11614913) polymorphism using a polymerase chain reaction-restriction fragment-length polymorphism (PCR-RFLP) approach. Results: The frequency of the miR-196a2 (rs11614913) T allele in con ...[more]
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