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ABSTRACT: Background
In addition to the core symptoms, attention deficit hyperactivity disorder (ADHD) is associated with poor emotion regulation. There is some evidence that children and young adults with ADHD have lower omega-3 levels and that supplementation with omega-3 can improve both ADHD and affective symptoms. We therefore investigated differences between ADHD and non-ADHD children in omega-3/6 fatty acid plasma levels and the relationship between those indices and emotion-elicited event-related potentials (ERPs).Methods
Children/adolescents with (n=31) and without ADHD (n=32) were compared in their plasma omega-3/6 indices and corresponding ERPs during an emotion processing task.Results
Children with ADHD had lower mean omega-3/6 and ERP abnormalities in emotion processing, independent of emotional valence relative to control children. ERP abnormalities were significantly associated with lower omega-3 levels in the ADHD group.Conclusions
The findings reveal for the first time that lower omega-3 fatty acids are associated with impaired emotion processing in ADHD children.
SUBMITTER: Gow RV
PROVIDER: S-EPMC5559876 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Gow Rachel V RV Sumich Alexander A Vallee-Tourangeau Frederic F Crawford Michael Angus MA Ghebremeskel Kebreab K Bueno Allain A AA Hibbeln Joseph R JR Taylor Eric E Wilson Daniel A DA Rubia Katya K
Prostaglandins, leukotrienes, and essential fatty acids 20130506 6
<h4>Background</h4>In addition to the core symptoms, attention deficit hyperactivity disorder (ADHD) is associated with poor emotion regulation. There is some evidence that children and young adults with ADHD have lower omega-3 levels and that supplementation with omega-3 can improve both ADHD and affective symptoms. We therefore investigated differences between ADHD and non-ADHD children in omega-3/6 fatty acid plasma levels and the relationship between those indices and emotion-elicited event- ...[more]