Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study.

ABSTRACT:

Objectives

To determine if the reduction of visceral adipose tissue (VAT) volume by lifestyle intervention improved risk factors for cardiovascular disease (CVD) independent of weight loss amount.

Design

Ancillary study of randomized-controlled trial.

Setting

Data analysis using multivariable regression models.

Participants

Participants of the Look AHEAD (Action for HEAlth in Diabetes) Fatty Liver Ancillary Study.

Main outcome measures

Correlations between changes in VAT and in CVD risk factors, while adjusting for weight loss and treatment (intensive lifestyle intervention [ILI] vs. diabetes support and education [DSE]).

Results

Of 100 participants analyzed, 52% were women, and 36% were black, with a mean age of 61.1 years. In the DSE group, mean

SUBMITTER: Sanguankeo A 

PROVIDER: S-EPMC5573136 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature