Global Screening of Salmonella enterica Serovar Typhimurium Genes for Desiccation Survival.

ABSTRACT: Salmonella spp., one of the most common foodborne bacterial pathogens, has the ability to survive under desiccation conditions in foods and food processing facilities for years. This raises the concerns of Salmonella infection in humans associated with low water activity foods. Salmonella responds to desiccation stress via complex pathways involving immediate physiological actions as well as coordinated genetic responses. However, the exact mechanisms of Salmonella to resist desiccation stress remain to be fully elucidated. In this study, we screened a genome-saturating transposon (Tn5) library of Salmonella Typhimurium (S. Typhimurium) 14028s under the in vitro desiccation stress using transposon sequencing (Tn-seq). We identified 61 genes

SUBMITTER: Mandal RK 

PROVIDER: S-EPMC5596212 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature