Ontology highlight
ABSTRACT:
SUBMITTER: Bansal D
PROVIDER: S-EPMC5611960 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Development (Cambridge, England) 20170814 17
Identifying key cellular events that facilitate stem cell function and tissue organization is crucial for understanding the process of regeneration. Planarians are powerful model system to study regeneration and stem cell (neoblast) function. Here, using planaria, we show that the initial events of regeneration, such as epithelialization and epidermal organization are critically regulated by a novel cytoplasmic poly A-binding protein, SMED-PABPC2. Knockdown <i>of smed-pabpc2</i> leads to defects ...[more]