Application of spin echoes in the regime of weak dephasing to T₁ -mapping of the lung.

ABSTRACT:

Purpose

This work presents an approach to mapping the entire lung's proton density and T₁ within a single breath-hold and analyzes the apparent T₁ when exciting with a spin echo generating pulse in comparison to a standard gradient echo acquisition.

Methods

An inversion-recovery SNAPSHOT-FLASH sequence with a stack-of-stars k-space readout with a golden angle increment was modified to use a spin echo generating radiofrequency-pulse for excitation. Data of five volunteers were acquired on a 3T scanner and image reconstruction was performed by an iterative algorithm adopted from MR-Fingerprinting.

Results

The feasibility of acquiring quantitative maps of the entire lung with a resolution of 5 × 5 × 10 mm within 7.5 s is demonstrated. It is shown th

SUBMITTER: Asslander J 

PROVIDER: S-EPMC5645219 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature