Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

ABSTRACT:

Background

Adults with bipolar disorder (BD) have higher rates of substance use disorders (SUDs) compared to the general population. SUD rates in young offspring/relatives of BD probands, as well as factors which drive those rates, are not as well-characterized.

Methods

We aimed to examine SUD prevalence among adolescent/young adult offspring and relatives of probands with and without BD. Data were collected from five sites in the US and Australia during 2006-2011. Youth offspring/relatives ("Relatives of BD probands;" n=267; mean age=16.8years; ±2.9S.D.), identified through a proband family member with DSM-IV BD (Type I or II), were compared to offspring/relatives of control probands ("relatives of control probands;" n=149; mean age=17.4years; ±2.9S.D.). Logistic regression

SUBMITTER: Hulvershorn LA 

PROVIDER: S-EPMC5647650 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature