Human Gut Microbiota Associated with Obesity in Chinese Children and Adolescents.

ABSTRACT:

Objective

To investigate the gut microbiota differences of obese children compared with the control healthy cohort to result in further understanding of the mechanism of obesity development.

Methods

We evaluated the 16S rRNA gene, the enterotypes, and quantity of the gut microbiota among obese children and the control cohort and learned the differences of the gut microbiota during the process of weight reduction in obese children.

Results

In the present study, we learned that the gut microbiota composition was significantly different between obese children and the healthy cohort. Next we found that functional changes, including the phosphotransferase system, ATP-binding cassette transporters, flagellar assembly, and bacterial chemotaxis were overrepresented, while gly

SUBMITTER: Hou YP 

PROVIDER: S-EPMC5682041 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature