Ontology highlight
ABSTRACT:
SUBMITTER: Skinner OS
PROVIDER: S-EPMC5726920 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Nature chemical biology 20171113 1
Protein complexes exhibit great diversity in protein membership, post-translational modifications and noncovalent cofactors, enabling them to function as the actuators of many important biological processes. The exposition of these molecular features using current methods lacks either throughput or molecular specificity, ultimately limiting the use of protein complexes as direct analytical targets in a wide range of applications. Here, we apply native proteomics, enabled by a multistage tandem M ...[more]