Influence of hiatal hernia and male sex on the relationship between alcohol intake and occurrence of Barrett's esophagus.

ABSTRACT:

Background

The association of alcohol intake with the incidence of Barrett's esophagus (BE) has been inconsistent. Although hiatal hernia and male sex are well-known risk factors of BE, its effect on the association of alcohol intake with the incidence of BE remains unknown.

Aim

To investigate whether the influence of alcohol intake on the occurrence of BE might differ depending on male sex and presence of hiatal hernia.

Methods

We utilized a database of 8031 patients that underwent upper endoscopy for health screening in a prospective, multicenter, cohort study (the Upper Gastro Intestinal Disease study). The incidence of endoscopic columnar-lined esophagus (eCLE; endoscopically diagnosed BE) was the outcome variable. Multivariable logistic regression analysis was co

SUBMITTER: Masuda A 

PROVIDER: S-EPMC5814023 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature