Pre-hospital frailty and hospital outcomes in adults with acute respiratory failure requiring mechanical ventilation.

ABSTRACT:

Purpose

We aimed to estimate the independent effect of pre-hospital frailty (PHF) on hospital mortality and prolonged hospital length of stay (pLOS) while adjusting for other patient level factors.

Methods

This is a cohort study of hospitalized adults with acute respiratory failure (ARF) who required invasive mechanical ventilation for ≥24h in 2013. We used inpatient/outpatient claims from a list of diagnoses from the year before index hospital admission to define PHF. Differences in characteristics/outcomes by PHF were explored using descriptive statistics; multivariable logistic regression was used to estimate association between PHF and hospital outcomes.

Results

Among 1157 patients (mean age (standard deviation) 67.1 [16.4]), 53.2% had PHF. PHF was independently a

SUBMITTER: Hope AA 

PROVIDER: S-EPMC5831479 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature