Tranexamic acid increases early perioperative functional outcomes after total knee arthroplasty.

ABSTRACT:

Background

The purpose of this study was to investigate the influence of tranexamic acid (TXA) on functional outcomes in the immediate postoperative period after total knee arthroplasty (TKA). We hypothesized that the known benefits of TXA would confer measurable clinical improvements in physical therapy (PT) performance, decrease pain, and decrease hospital length of stay (LOS).

Methods

We retrospectively analyzed 560 TKA patients, including 280 consecutive patients whose surgery was performed before the initiation of a standardized TXA protocol and the first 280 patients who received TXA after protocol initiation. Outcome measurements included postoperative changes in hemoglobin and hematocrit, LOS, pain scores, destination of discharge, and steps ambulated with PT over 5

SUBMITTER: Grosso MJ 

PROVIDER: S-EPMC5859255 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature