Cost-Effectiveness of Competing Treatment Strategies for Clostridium difficile Infection: A Systematic Review.

ABSTRACT: BACKGROUND Clostridium difficile infection (CDI) presents a substantial economic burden and is associated with significant morbidity. While multiple treatment strategies have been evaluated, a cost-effective management strategy remains unclear. OBJECTIVE We conducted a systematic review to assess cost-effectiveness analyses of CDI treatment and to summarize key issues for clinicians and policy makers to consider. METHODS We searched PubMed and 5 other databases from inception to August 2016. These searches were not limited by study design or language of publication. Two reviewers independently screened the literature, abstracted data, and assessed methodological quality using the Drummond and Jefferson checklist. We extracted data on study characteristics, type of CDI, treatment characteri

SUBMITTER: Le P 

PROVIDER: S-EPMC5869164 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature